J Dermatol Plast Surg | Volume 4, Issue 1 | Research Article | Open Access
Eman El Morsy, Tarek M Hussien and Omnia M Abdel Maksoud*
Department of Dermatology, Venereology and Andrology, Alexandria University, Egypt
*Correspondance to: Omnia M Abdel MaksoudFulltext PDF
Introduction: Scar formation is an inevitable consequence of wound healing from either a traumatic or a surgical intervention in which the normal skin is replaced by a fibrous tissue, although Scar formation is beneficial in wound healing, it can lead to cosmetic problems, psychological and financial issues. Material and
Method: Forty patients were divided into two groups, Group A was subjected to needling technique followed by intralesional injection of triamicinolone acetonide (40 mg/ml) in the same session once/month for three months, while group B was subjected to intralesional botulinum toxin A injection once/month for three months. An independent physician evaluator assessed the treatment outcomes using Vancouver Scar Scale (VSS) and Quartile grading scale (slight improvement: 0% to 25%; moderate: 25% to 50%; significant: 50% to 75%; marked: 75% to 100% improvement).
Results: There were statistically significant differences between the 2 groups as regards the VSS (p=0.023). Average percentage changes of VSS were 84.47% ± 14.34% in group A while was 72.71% ± 14.60% in group B. Improvement was evident as regards vascularity, pliability, height and pigmentation in both groups after treatment with better results in group A. Patient’s subjective satisfaction scores paralleled the physician’s objective evaluation.
Conclusion: Microneedling combined IL-CST injection is safe and effective modality and its results was superior to IL-BTA in the treatment of HTSs and keloids.
Needling; Steroid; Botox
El Morsy E, Hussien TM, Abdel Maksoud OM. Needling Combined with Intralesional Corticosteroid Injections Compared to Intralesional Botulinum Toxin A Injections in the Treatment of Hypertrophic Scars and Keloids. J Dermatol Plast Surg. 2019; 3(1): 1021.