Am J Pharmacol | Volume 7, Issue 1 | Review Article | Open Access
Abdel-Sater KA*
Department of Dentistry, Mutah University, Jordon
*Correspondance to: Khaled A Abdel-Sater
Fulltext PDFBackground: The recent sub-classification of diabetes into five different subtypes or clusters, were known as Severe Autoimmune Diabetes (SAID), Severe Insulin-Deficient Diabetes (SIDD), Severe Insulin-Resistant Diabetes (SIRD), Mild Obesity-related Diabetes (MOD), and Mild Age-Related Diabetes (MARD). This new classification was based on six clinical variants: Age, body-mass index at diagnosis, glycosylated hemoglobin, glutamic acid decarboxylase antibodies, homeostasis model assessment 2 beta and IR.
This new classification helps i) reclassification of the accurate different forms and subtypes and their clinical characteristics, ii) better understanding of the pathophysiology of each type iii) drawing the prognosis and predict diabetic complications and iv) selecting the most suitable anti-diabetic treatments for each type based on the pathophysiology.
Objective: This review aimed to provide a short overview of new diabetes classification and rearrange of clinical characteristics, disease progression and treatment for each subtype.
DM clusters; SAID; SIDD; SIRD; MOD; MARD
Abdel-Sater KA. New Paradigms of Diabetes Classification: Implications for Complication. Am J Pharmacol. 2024; 7(1): 1039..