World J Psychiatry Ment Health Res | Volume 4, Issue 1 | Research Article | Open Access

Dopamine Receptor Binding in the Amygdala Interacts with Gender: A PET Study Using AMPT and [18F]fallypride

Patrizia Riccardi^1*, Xianming Carroll² and Larry Cahill³

Department of Psychiatry, Manhattan Psychiatric Center, MPC, USA
Department of Community Medicine, Mercer University, USA
Department of Neurobiology, University of California, Irvine, USA

^*Correspondance to: Patrizia Riccardi 

Abstract

Dopaminergic neurotransmission plays an important role in many psychiatric disorders which show sex differences in incidence, clinical course, and treatment outcomes. We examined whether PET studies using [18F]fallypride performed prior to and following Alphamethylparatyrosine (AMPT) administration could be used to estimate sex differences in baseline Dopamine D2/D3 receptors (D₂D₃r) occupancy.

Keywords:

Dopamine; PET; Humans; [18F]fallypride; Alphamethylparatyrosine challenge

Citation:

Riccardi P, Carroll X, Cahill L. Dopamine Receptor Binding in the Amygdala Interacts with Gender: A PET Study Using AMPT and [18F]fallypride. World J Psychiatry Ment Health Res. 2020; 4(1): 1022..