World J Depress Anxiety | Volume 2, Issue 1 | Case Report | Open Access

Level and Factors Associated with Depression among Thyroid Patients at a Tertiary Care Hospital in Pakistan

Sundas Rehman1, Nafees Ahmad2*, Abdul Wahid2, Asad Khan2 and Qaiser Iqbal2

1Department of Pharmacy and Health Sciences, University of Baluchistan Quetta, Pakistan
2Department of Pharmacy Practice, University of Baluchistan Quetta, Pakistan

*Correspondance to: Nafees Ahmad 

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Background: Patients with thyroid disorders are at greater risk of developing depression as per globally published data but in Pakistan there is scarcity of published literature regarding this domain of health science. To evaluate the level and factors associated with depression receiving treatment a tertiary care hospital.

Methodology: A cross-sectional study conducted at the outpatient department of Centre for Nuclear Medicine and Radiotherapy Quetta. A total of 341 eligible subjects were enrolled. Patients’ socio-demographic and clinical data was collected via a purpose developed data collection form. Depression level was assessed through validated Urdu version of 21-items Hamilton rating scale
for depression. Data was analyzed by SPSS 20. Final model of factors associated with high score of depression were analyzed through multiple linear regression. A p-value <0.05 was statistically significant.

Results: Mean age of subjects enrolled was 34.03 ± 10.06 years. Majority being females (80.6%). All patients (100%) were depressed. Most of them very severe (46%) followed by severe (36.4%) and moderate depression (17.6%). Upon multiple linear regression, patients’ age of 18 years to 30 years (P=0.001, B=2.629), illiteracy (P<0.001, B=3.493), drug abuse (P= <0.001, B=3.711) and thyroid disease for >10 years (P=0.002, B=3.384) were associated with higher depression scores.

Conclusion: The prevalence of depression in thyroid patients was high. These patients should be evaluated for depression regularly. High risk groups should receive enhanced clinical management.


Depression; Thyroid; Pakistan; Quetta; Tertiary care


Rehman S, Ahmad N, Wahid A, Khan A, Iqbal Q. Level and Factors Associated with Depression among Thyroid
Patients at a Tertiary Care Hospital in Pakistan. World J Depress Anxiety. 2020;2(1):1005..

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