Oncol Case Rep J | Volume 6, Issue 1 | Case Report | Open Access

Alveolar Rhabdomyosarcoma of the Prostate Presenting as Lower Urinary Tract Symptoms in a Young Adult

Uy TGC^*, Alcala GRM, Bocobo JC, Bingcang CLA, Pascual-Panganiban AMM, EvangelistaGorospe AS, Panganiban JZK and Imasa MSB

Department of Medicine, St. Luke’s Medical Center, Philippines

^*Correspondance to: Tiffany Grace C Uy 

Abstract

Introduction: Rhabdomyosarcoma (RMS) of the prostate in young adults is exceedingly rare.
Case Report: A 27-year-old male presented with 2-month history of lower urinary tract symptoms. Prostate was enlarged smooth nontender with no nodularity’s. PET-CT showed prominent iliac chain lymph nodes, enlarged spleen and multiple osseous lytic and blastic lesions. Histopathology of prostate tissues revealed round cell malignancy, positive for Desmin and Myogenin. Archer analysis was positive for PAX3:FOXO1 fusion gene. Patient was diagnosed as Alveolar Rhabdomyosarcoma of the prostate Stage IVB (cT4N1M1B-bone). He underwent Vincristine, Dactinomycin and Cyclophosphamide (VAC) chemotherapy.
Conclusion: Prostatomegaly and splenomegaly are unusual findings in a young male. A high index of suspicion will help in detecting prostatic malignancy before it is too late

Keywords:

Lower urinary tract symptoms; Prostate cancer; Rhabdomyosarcoma

Citation:

Uy TGC, Alcala GRM, Bocobo JC, Bingcang CLA, Pascual-Panganiban AMM, Evangelista-Gorospe AS, et al. Alveolar Rhabdomyosarcoma of the Prostate Presenting as Lower Urinary Tract Symptoms in a Young Adult. Oncol Case Report J. 2023; 6(2): 1056..