Oncol Case Rep J | Volume 6, Issue 1 | Case Report | Open Access

Warm Autoimmune Hemolytic Anemia (wAIHA) in Patient with Diffuse Large B-Cell Lymphoma (DLBCL): A Case Report

Rajabto W^1,4, Harahap A², Anggraeni TD³ and Pyrhadistya M^1*

¹Department of Internal Medicine, Dr. Cipto Mangunkusumo General Hospital, University of Indonesia, Indonesia
²Department of Anatomical Pathology, Dr. Cipto Mangunkusumo General Hospital, University of Indonesia, Indonesia
³Department of Obstetrics and Gynecology, Dr. Cipto Mangunkusumo General Hospital, University of Indonesia, Indonesia
⁴Division of Hematology-Medical Oncology, Dr. Cipto Mangunkusumo General Hospital, University of Indonesia, Indonesia

^*Correspondance to: Maria Pyrhadistya 

Abstract

Warm Autoimmune Hemolytic Anemia (wAIHA) can be primary or secondary. In this case, we found DLBCL as the underlying disease of wAIHA. We report a 50-year-old female presented with fatigue, fever, and dyspnea when activity for 3 months before admission. Physical examination showed both of the conjunctiva were pale and multiple lymphadenopathy at Regio colli, axilla, and inguinal bilateral. Coombs test revealed IgG and C3d. The result of histopathology and immunohistochemistry of excisional biopsy was DLBCL. We administered blood transfusion and steroid for wAIHA and treated the underlying disease DLBCL with R-CHOP, we found complete remission of both wAIHA and DLBCL.

Keywords:

wAIHA; DLBCL; Blood transfusion; Steroid; R-CHOP

Citation:

Rajabto W, Harahap A, Anggraeni TD, Pyrhadistya M. Warm Autoimmune Hemolytic Anemia (wAIHA) in Patient with Diffuse Large B-Cell Lymphoma (DLBCL): A Case Report. Oncol Case Report J. 2023; 6(1): 1052..