J Hematol Mult Myeloma | Volume 4, Issue 1 | Research Article | Open Access

Platelet Indices in the Diagnosis of Acute Appendicitis

Lalhruaitluanga and Chawngthu Vanlalhlua*

Department of Surgery, Zoram Medical College, India

*Correspondance to: Chawngthu Vanlalhlua 

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Background: The aim of this study was to evaluate the diagnostic value of platelet indices (mean platelet volume and platelet distribution width) and its predictive value in determining the complication/severity of acute appendicitis. Method: This study comprised of 126 adult patients of Acute Appendicitis who were operated in the department of Surgery, Zoram Medical College, Falkawn during the period of two years starting from March 2017 to April 2018. Patients below 12 years, pregnant female, patients on steroid/ chemotherapy, immuno-compromised patients and those who are not willing to participate were excluded. Results: The Mean Platelet Volume (MVP) of less than 7.6 was found in 73 (57.9%). The mean MPV was 7.98 ± 1.29. Platelet Distribution Width (PDW) was more than 18 patients (23.7%). Out of which 16 and 14 were females and males respectively. The mean PDW was 16.99 ± 2.30. Total Leucocyte Count (TLC) was raised (taking 1,100 as cut-off value) in 82 patients (65.1%). 11 patients were associated with perforated appendix and 10 patients had intraoperative finding of periappendiceal collection. Gangrenous appendix was found in 16 (12.7%) patients. Conclusion: MVP did not have higher sensitivity compared with TLC in the diagnosis of acute appendicitis but PDW have higher sensitivity than TLC and is found higher in complicated appendicitis. Therefore, PDW may be used in the diagnosis of acute appendicitis and has a significant role in predicting complicated appendicitis.


Acute appendicitis; Mean platelet volume; Platelet distribution width; Total leucocyte count; Perforated appendix


Lalhruaitluanga, Vanlalhlua C. Platelet Indices in the Diagnosis of Acute Appendicitis. J Hematol Mult Myeloma. 2019; 4(1): 1021..

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