J Hematol Mult Myeloma | Volume 7, Issue 1 | Case Report | Open Access

IGH-MECOM (EVI1) Rearrangement in Therapy-Related Myeloid Neoplasm

Xiao R*, Templeton S, Harris K and Shi Y

Department of Pathology, Montefiore Medical Center/Albert Einstein College of Medicine, USA

^*Correspondance to: Ruobing Xiao 

Abstract

Rearrangements involving EVI1 (MECOM) include in (3) (q21q26), t (3;3) (q21; q26), and other translocations involving 3q26, which result in overexpression of the EVI1 oncogene and are associated with aggressive myeloid neoplasms, including therapy-related Acute Myeloid Leukemia (AML) and Myelodysplastic Syndromes (MDS).

Keywords:

Myeloid neoplasm; Myelodysplastic syndromes; Leukemia

Citation:

Xiao R, Templeton S, Harris K, Shi Y. IGH-MECOM (EVI1) Rearrangement in Therapy-Related Myeloid Neoplasm. J Hematol Mult Myeloma. 2026; 7(1): 1032.