J Clin Nephrol Kidney Dis | Volume 3, Issue 2 | Case Report | Open Access

Vitamin B12 Deficiency Presenting with Bilateral Vocal Fold Paralysis

Can Huzmeli1*, Eylem Eliacık2, Barış Doner1, Mustafa Saglam1, Mustafa Karakus3 and Ferhan Candan4

1Department of Nephrology, Necip Fazıl City Hospital, Turkey
2Department of Hematology, Necip Fazıl City Hospital, Turkey
3Department of Otolaryngology, Necip Fazıl City Hospital, Turkey
4Department of Nephrology, Cumhuriyet University, Turkey

*Correspondance to: Can Hüzmeli 

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Background: Vitamin B12 deficiency often leads to hematological and neuropsychiatric disorders. Vitamin B12 deficiency usually begins with megaloblastic anemia. Neurological symptoms often occur later.
Case Report: We describe a case of 55-years old type 2 diabetic male patient with rare cause of bilateral vocal fold paralysis due to vitamin B 12 deficiency. He was under treatment of insulin, metformin and valsartan for 5 years.
Conclusion: Physcians should be kept in mind that long term use of metformin could result vitamin B12 deficiency when assesing the etiology of focal fold paralysis. We tried to discuss the recovering case after vitamin B12 treatment in the context of the literature.


Vitamin B12 deficiency; Vocal fold paralysis; Metformin


Huzmeli C, Eliacık E, Doner B, Saglam M, Karakus M, Candan F. Vitamin B12 Deficiency Presenting with Bilateral Vocal Fold Paralysis. J Clin Nephrol Kidney Dis. 2018; 3(2): 1018.

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