J Clin Nephrol Kidney Dis | Volume 3, Issue 2 | Case Report | Open Access

Atheroembolic Disease and Antineutrophil Cytoplasmic Autoantibodies

Betancourt L, Ponz E and Almirall J*

Department of Nephrology and Medicine, Parc Tauli Sabadell, University Hospital, Spain

*Correspondance to: Jaume Almirall 

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Atheroembolic disease is a systemic disorder associated with diffuse atherosclerosis. The most common triggers are endovascular manipulation like angiography and therapeutic procedures such as cardiovascular surgery or fibrinolytic therapies; also, it may occur spontaneously. Common clinical manifestations include skin lesions and the systemic symptom of the disease can mimic systemic vasculitis. A few anecdotal cases have been reported in which atheroembolic disease was accompanied by a positive perinuclear antineutrophil cytoplasmatic antibody in the absence of clinical or histological evidence of vasculitis.
We report a case of atheroembolic disease diagnosed by renal biopsy in the presence of positive perinuclear antineutrophil cytoplasmatic antibody. The patient was treated whit steroid for 3 months without recovery of renal function. We also review the cases reported in the literature.


Betancourt L, Ponz E, Almirall J. Atheroembolic Disease and Antineutrophil Cytoplasmic Autoantibodies. J Clin Nephrol Kidney Dis. 2018; 3(2): 1017.

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