Betancourt L, Ponz E and Almirall J*
Department of Nephrology and Medicine, Parc Tauli Sabadell, University Hospital, SpainFulltext PDF
Atheroembolic disease is a systemic disorder associated with diffuse atherosclerosis. The most common triggers are endovascular manipulation like angiography and therapeutic procedures such as cardiovascular surgery or fibrinolytic therapies; also, it may occur spontaneously. Common clinical manifestations include skin lesions and the systemic symptom of the disease can mimic systemic vasculitis. A few anecdotal cases have been reported in which atheroembolic disease was accompanied by a positive perinuclear antineutrophil cytoplasmatic antibody in the absence of clinical or histological evidence of vasculitis.
We report a case of atheroembolic disease diagnosed by renal biopsy in the presence of positive perinuclear antineutrophil cytoplasmatic antibody. The patient was treated whit steroid for 3 months without recovery of renal function. We also review the cases reported in the literature.
Betancourt L, Ponz E, Almirall J. Atheroembolic Disease and Antineutrophil Cytoplasmic Autoantibodies. J Clin Nephrol Kidney Dis. 2018; 3(2): 1017.