J Cancer Clin | Volume 1, Issue 1 | Research Article | Open Access

Obstructive Jaundice: A Rare Presentation of Non-Hodgkin Lymphoma in a Child

Apostolos Pourtsidis1*, Smaragda Papachristidou1, Marina Servitzoglou1, Dimitrios Doganis1, Konstantina Kapetaniou1, Maria Nikita1, Evgenia Magkou1, Dimitrios Kipraios2, Astero Malama3, Panagiota Giamerelou4 and Margarita Baka1

1Department of Oncology, P & A Kyriakou Children’s Hospital, Greece
2Department of Gastroenterology, Agios Savvas Hospital, Greece
3Department of Radiology, Aghia Sophia Children’s Hospital, Greece
4Department of Pathology, P & A Kyriakou Children’s Hospital, Greece

*Correspondance to: Apostolos Pourtsidis 

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Obstructive jaundice is an unusual manifestation of a Non-Hodgkin lymphoma in a child. Although Burkitt lymphoma is the most common histological type of Non-Hodgkin lymphomas of the abdomen, diffuse Large B-cell Lymphoma can occur as well. We report a case of a 14-year old girl who presented with obstructive jaundice due to non-Hodgkin Lymphoma encasing the common bile duct. Imaging studies aided to diagnosis. Histological examination of the specimen, obtained by laparoscopic surgery, revealed diffuse Large B-cell Lymphoma. Patient received chemotherapy according to FAB LMB 96 protocol. Bilirubin rates normalized after the initial course of chemotherapy. She concluded her treatment and remains free of disease. In conclusion, obstructive jaundice is a rare type of presentation of diffuse Large B-cell Lymphomas but with high clinical suspicion, proper imaging studies and a proper biopsy, diagnosis can be obtained.


Pourtsidis A, Papachristidou S, Servitzoglou M, Doganis D, Kapetaniou K, Nikita M, et al. Obstructive Jaundice: A Rare Presentation of Non-Hodgkin Lymphoma in a Child. J Cancer Clin. 2018; 1(1): 1004.

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