Rozita Mohd and Lim Kuan Yee*
Nephrology Unit, Medical Department, University Kebangsaan Malaysia Medical Centre, MalaysiaFulltext PDF
Thrombotic Thrombocytopenic Purpura (TTP) is characterized by a pentad of microangiopathic hemolytic anemia, thrombocytopenia, acute kidney injury, neurological symptoms, and fever. It is one of the phenotypes of Thrombotic Microangiopathy (TMA), commonly described in adults. The etiology of TTP is either due to congenital or acquired deficiency of plasma enzyme ADAMTS13 which is associated with female gender, black ethnicity, use of desmopressin, and pregnancy. We describe a rare case of drug induced TTP with selective cyclooxygenase inhibitor etoricoxib that was used for pain control post operation.
Thrombotic Thrombocytopenic Purpura (TTP); Microangiopathic hemolytic anemia; Thrombocytopenia; Acute kidney injury; Etoricoxib
Mohd R, Yee LK. Etoricoxib Induced Thrombotic Thrombocytopenic Purpura. Int J Fam Med Prim Care. 2020;1(6):1028.