Ann Trauma Acute Care | Volume 3, Issue 1 | Case Report | Open Access

Simultaneous 111In-WBC and 99mTc-SC SPECT/CT Clearly Delineates Infection Sites

Alex M Mayeux1 , Nour Nakrour2 , Anna Y Li3 , David H Ballard4 and Zhiyun Yang2*

1Department of Medicine, Louisiana State University Health-Shreveport, USA 2Department of Radiology; Louisiana State University Health-Shreveport, USA 3Department of Radiology; Stanford University School of Medicine-Stanford, USA 4Department of Radiology, Washington University School of Medicine-St Louis, USA

*Correspondance to: Zhiyun “Jane” Yang 

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A 22-year-old man sustained a complex left ankle fracture following a motor vehicle collision and underwent external and internal fixation with transfixation-pinning. Several weeks after surgery, the patient presented with clinical concerning for infection at the fracture sites. Initial radiographic evaluation of the left lower extremity showed no evidence of osteomyelitis. The patient underwent SPECT/CT with a novel imaging protocol, using simultaneous acquisition of 111In-WBC and 99mTcSC SPECT/CT, which clearly delineated the infection sites along the orthopedic hardware track and adjacent soft tissues. This new combined SPECT/CT protocol offers advantages of shorter scanning time, easy patient positioning, expedited diagnostic workup, and more accurate localization of infection sites compared to the conventional protocol of separately acquiring 111In-WBC and 99mTcSC SPECT/CT images


111In-oxinelabeled leukocytes; SPECT-CT; 99mTc-sulfur colloid; Intramedullary hardware; Infection


Mayeux AM, Nakrour N, Li AY, Ballard DH, Yang Z. Simultaneous 111In-WBC and 99mTc-SC SPECT/CT Clearly Delineates Infection Sites. Ann Trauma Acute Care. 2019;3(1):1017.

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