Ann Surg Case Rep | Volume 7, Issue 1 | Review Article | Open Access

The Association between Tumor Microenvironment Collagen and Liver Metastasis in Colorectal Cancer

Fan J, Zhu Q, Nie J and Yang D^*

Department of General Surgery, Guangdong Provincial Key Laboratory of Precision Medicine for Gastrointestinal
Tumor, Nanfang Hospital, The First School of Clinical Medicine, Southern Medical University, China

^*Correspondance to: Dinghua Yang, 

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Abstract

The colon is an organ rich in collagen, while the liver is an organ deficient in collagen. The tissue microenvironment of the two organs differs significantly, but the incidence of liver metastasis in colorectal cancer is high. Besides vascular drainage factors, the changes in collagen occurring in the liver during the process of colorectal cancer liver metastasis are also very important. This article aims to discuss the characteristics of collagen changes in the premetastatic stage, liver colonization, and intrahepatic metastasis process of colorectal cancer liver metastasis.

Keywords:

Collagen; Tumor microenvironment; Colorectal-liver metastasis

Citation:

Fan J, Zhu Q, Nie J, Yang D. The Association between Tumor Microenvironment Collagen and Liver Metastasis in Colorectal Cancer. Ann Surg Case Rep. 2024; 7(1): 1088..