Ann Plast Reconstr Surg | Volume 7, Issue 1 | Research Article | Open Access

The Effect of Pulsed Electromagnetic Fields on Rat Muscle Ischemia-Perfusion Model

Yuvacı AU1*, Yavuz OM1, Pelit A2, Taştekin B2 and Sapmaz T3

1Department of Plastic, Reconstructive and Aesthetic Surgery, Cukurova University, Turkey
2Department of Biophysics, Cukurova University, Turkey
3Department of Histology and Embryology, Cukurova University, Turkey

*Correspondance to: Ahmet Umut Yuvacı 

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Ischemia is defined as the reduction or cessation of blood flow to a tissue. Reperfusion is maintaining the blood flow to the tissue again. These changes in blood flow to the tissues cause damage. This damage depends on the cause, duration, and severity of ischemia, as well as reperfusion. It is so-called Ischemia-Reperfusion (I-R) injury. Although I-R injury has a complex pathophysiological process accompanied by many mechanisms, the elucidation of these mechanisms has led to a search for solutions in order to prevent the damage. Despite numerous surgical and pharmacological studies, a safe treatment that can reverse I-R damage has not been found yet. Pulsed Electromagnetic Field (PEMF) therapy is a treatment modality that has been used for many years and has proven its effectiveness on bone healing, wound healing, tissue regeneration, and anti-inflammatory properties. Our study aims to examine the effects of PEMF application on skeletal muscle damage after I-R injury in the lower extremity of the rat.


Ischemia reperfusion injury; Pulsed electromagnetic field; Skeletal muscle


Yuvacı AU, Yavuz OM, Pelit A, Taştekin B, Sapmaz T. The Effect of Pulsed Electromagnetic Fields on Rat Muscle Ischemia-Perfusion Model. Ann Plast Reconstr Surg. 2023; 7(1): 1105..

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