Ann Infect Dis Epidemiol | Volume 9, Issue 1 | Research Article | Open Access

Frequency of Immunogical Markers and Hepatitis B Immunization of Health Personnel and Health Science Students in Conakry, Guinea

Amadou Sadio BAH1,2#*, Alimou Camara3,4#, Mamoudou Conde1, Mariama Sadio Diallo3,5, Oumar Mouctar Diallo3, Doufin Traore3, Abraham Kamano1, Alphonse Tamba Tolno1, Mamadou C. Diallo1, Kaba Kourouma1,3, Sanaba Boubaly4, Mohamed Sahar Traore2,3, Abdoulaye Toure3 and Fodé Amara Traore1,3

1National Institute of Public Health, Ministry of Health and Public Hygiene, Guinea  2Guinean Research Institute of Applied Biology, Ministry of Higher Education Scientific Research and Innovation, Guinea  3Faculty of Health Sciences and Technology, Gamal Abdel Nasser University, Conakry, Guinea  4Virology Research Center, Ministry of Higher Education, Scientific Research and Innovation, Guinea  5Centre D’Excellence Afrcaine pour le Controle des Maladies Transmissibles, Gamal Abdel Nasser University, Conakry, Guinea #Equally contribution

*Correspondance to: Amadou Sadio BAH 

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Abstract

Introduction: The hepatitis B virus (HBV) is a DNA virus responsible for inflammation of the liver. It is transmitted by unprotected sexual intercourse with an infected person, by contact with infected blood, and vertically from mother to child. The risk of contagion is very high in healthcare environments, especially for under-equipped and less experienced staff.  Objective: The aim of this study was to determine seroprevalence and risk factors for HBV transmission among health science students and health care staff in Conakry.  Methods: This was a prospective cohort involving staff from Conakry's three hospitals and medical centers, as well as health science students from Conakry's public and private universities and health schools, i.e. 24 facilities. The data collected concerned socio-demographic information, vaccination status and 2ml of blood in a tube without anticoagulant, on which the AgHBs was tested and the rest transported to the immuno-serology laboratory of the Institut National de Santé for further testing. Statistical analyses were performed using SPSS software. The p-value was calculated to determine the existence of a statistically significant relationship between the study variables.  Results: A total of 3041 staff and students in the health sciences participated in the study, of whom 257 were HBsAg positive (8.5%). All these AgHBs-positive participants also carried total anti-HBc antibodies and 2.3% were HBeAg carriers.  Conclusion: Hepatitis B is a public health problem in universities and health facilities in Conakry. A study extended to other regions of the country would provide a better picture of the extent of hepatitis B in Guinea.

Keywords:

Hepatitis B; Health science student; Health workers; Conakry; Guinea

Citation:

Amadou Sadio BAH, Camara A, Conde M, Diallo MS, Diallo OM, Traore D, et al. Frequency of Immunogical Markers and Hepatitis B Immunization of Health Personnel and Health Science Students in Conakry, Guinea. Ann Infect Dis Epidemiol. 2025; 9(1): 1073..

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