Ann Gynecol Obstetr Res | Volume 2, Issue 2 | Case Report | Open Access

Leiomyoadenomatoid Tumor of the Uterus: A Case Report of a Rare Entity

Saadia Makni*, Adnen Moussa, Manel Njima, Leila Njim and Abdelfatteh Zakhama

Department of Pathology, Fattouma Bourguiba University Hospital, Tunisia

*Correspondance to: Saadia Makni 

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Adenomatoid tumor is a benign neoplasm that occurs frequently in the wall of fallopian tubes in females. Leiomyoadenomatoid tumor of the uterus is a variant of adenomatoid tumor which is extremely rare and difficult to recognize on microscopic examination. We report here a case of a 37-year-old woman who presented with vaginal bleeding during the past 6 months. Pelvic ultrasonography revealed three masses in the myometrium. Laparoscopy transvaginal masses removal was performed under the clinical impression of uterine leiomyomas. Histological examination followed by immunohistochemistry straightened the diagnosis of leiomyoma in one mass and confirmed the presence of a biphasic proliferation: an adenomatoid component, which was immunoreactive with calretinin, intermingled with interlacing fascicles of neoplastic smooth muscle cells. Here in we report the fourteenth case of leiomyoadenomatoid tumor of the uterus. Ignorance of this rare entity may lead to false diagnoses, such as a malignant epithelial or mesothelial neoplasm, resulting in a more aggressive therapy.


Adenomatoid tumor; Leiomyoadenomatoid tumor; Uterus


Makni S, Moussa A, Njima M, Njim L, Zakhama A. Leiomyoadenomatoid Tumor of the Uterus: A Case Report of a Rare Entity. Ann Gynecol Obstetr Res. 2019; 2(2): 1012.

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