Am J Otolaryngol Head Neck Surg | Volume 6, Issue 6 | Research Article | Open Access

Randomized Controlled Trial and Analysis of ABR and EcochG Tests in Meniere’s Disease

Narendra BS

VAV Care Clinic and Sarvoday Hospital, India

*Correspondance to: Narendra BS 

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Purpose: 1. To determine and compare the wave III latency values on ABR test and SP/AP ratios on EcochG test in affected ears of Meniere’s disease with control group of healthy ears. 2. To bear the hypothesis of deviation of III wave latency values on ABR test in definite active Meniere’s disease as abnormal feature and compare with Electrocochleographic electro potential ratios in the same diseased subject group. Study Design: A prospective observational control study is done in clinically definite of active Meniere’s Disease (MD) between 2016-2020. There are 38 consecutive patients of unilateral MD (Group A) as per criteria laid upon by Barany’s society (1995) and 31 normal subjects (Group B). All the subjects undergo thorough clinical ear examination, PTA and ABR in both ears in group A and group B ears. EcochG is conducted for affected ears in group A and randomly selected ears in group B. The valued results of ABR and EcochG in group A are considered for comparison with each other’s for the possibility of cochlear hydrops; as well with group B with normative data. The relevant biostatistical tests are applied for further interpretations. Results: All 36 subjects of unilateral MD displayed abnormal findings for at least one test than the controlled 32 subjects. The cut off value on ABR for latency of wave III suggesting cochlear hydrops is 3.645 ms; while SP/AP ratio in EcochG is 0.5 suggesting the cochlear hydrops in MD. there was mutual agreement between the ABR and EcochG tests in 21/36 as affected ears and mutual agreement for as non-affected ears in 7/36 and neither agreement/disagreement in 8/36 ears. Conclusion: In affected ears of MD ABR test evaluation for wave III latency and SP/AP ratio on EcochG displayed significant valued differences from normative data obtained for. The sensitivity and specificity of EcochG is 71% and 81% while that of ABR test is 80% and 67% respectively and are found to be useful to diagnose MD.


ABR: Acoustic brainstem response; EcochG: Electrocochleogram; MD: Meniere’s Disease


Narendra BS. Randomized Controlled Trial and Analysis of ABR and EcochG Tests in Meniere’s Disease. Am J Otolaryngol Head Neck Surg. 2023; 6(6): 1250.

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