Am J Allergy Asthma Immunol Res | Volume 1, Issue 1 | Mini Review | Open Access

Discovering Biomarkers of Neutrophilic Asthma: A Researcher’s Perspective

Fu Qian Zhao, Ming Quan Shang, Shen Daofu and Lei Wang*

Department of Clinical Laboratory, Chifeng Municipal Hospital/Chifeng Clinical College of Inner Mongolia Medical University, China

*Correspondance to: Lei Wang 

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Abstract

Asthma is a chronic inflammatory disease of the airways characterized by inflammatory responses, airway hyperresponsiveness, reversible airway obstruction, and airway structural remodeling. It is a key therapeutic target for this inflammatory pathway, although neutrophilic airway inflammation occurs most often in steroid-insensitive asthma, severe asthma, asthma exacerbation, and occupational asthma. We currently lack biomarkers for the diagnosis of neutrophilic asthma. In this issue of allergy, asthma and immunology research, Bich et al. analyzed adult asthmatic patients and healthy control subjects, and found significant differences in serum SAA1 levels. From the perspective of basic research, our team puts forward some views and opinions on the problems and short comings of this research, and expects more researchers to pay attention to the research of asthma. We believe that the interrelationship between IL-6 and SAA1 in asthma is worth exploring despite some imprecisions in this study.

Keywords:

Neutrophilic asthma; SAA1; Biomarkers; IL-6

Citation:

Zhao FQ, Shang MQ, Daofu S, Wang L. Discovering Biomarkers of Neutrophilic Asthma: A Researcher’s Perspective. Am J Allergy Asthma Immunol Res. 2022; 1(1): 1004..

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